Acute impairment of early T cell activation following impediment of mitochondrial electron transport (LB166)
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چکیده
منابع مشابه
Original Contribution IMPAIRMENT OF THE MITOCHONDRIAL ELECTRON CHAIN TRANSPORT PREVENTS NF-kB ACTIVATION BY HYDROGEN PEROXIDE
A large body of work has been devoted to mechanisms leading to the activation of the transcription factor NF-kB in various cell types. Several studies have indicated that NF-kB activation by numerous stimuli depends on the intracellular generation of reactive oxygen species (ROS). In this report, we first demonstrated that inhibition of the electron transport chain by either rotenone or antimyc...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2014
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.28.1_supplement.lb166